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All mice were maintained under specific pathogen-free conditions under license and approval of local animal research ethics committee committee (Health Products Regulatory Authority [HPRA], Ireland) and European Union regulations

Discussion: Our findings suggest that CB-839 has limited efficacy in CLL treatment and shows limited synergy in combination with widely used CLL drugs

Metabolomics of fecal extracts detects altered metabolic activity of gut microbiota in ulcerative colitis and irritable bowel syndrome

The review will also address the critical implications of smoking in the context of liver transplantation, highlighting its influence on post-transplant outcomes